In this new edition of the acclaimed Dementia: Presentations, Differential Diagnosis, and Nosology, V. Olga B. Emery, Ph.D., and Thomas E. Oxman, M.D., bring together a distinguished group of medical authorities--including many who have done seminal research in this field--to discuss the spectrum of dementing disorders and explain their overlap, presentations, and differential diagnosis. The chapters present original data as well as material from the authors' clinical experiences. Current classification systems are evaluated and modified to better account for common presentations of dementia. Thoroughly revised, updated, and expanded, the second edition includes new material on neuroimaging, genetics, the role of inflammation in Alzheimer disease, retrophylogenesis in Alzheimer memory, and on AIDS dementia. In addition, each chapter includes a new section entitled describing clinical applications.
Contents:List of Contributors Acknowledgments List of Abbreviations IntroductionPART ONE: Background, Concepts, and Diagnostics1. Boundaries between Normal Aging and Dementia: Perspectives from Neuropsychological and Neuroimaging Investigations 2. The Spectrum of Dementias: Construct and Nosologic Validity 3. Diagnostic Procedures for Dementia PART TWO: Alzheimer Dementias4. The Neuropathology of Alzheimer Dementia 5. Neural Inflammatory Mechanisms in Alzheimer Syndrome 6. Clinical Subgroups of Alzheimer Disease 7. Progressive Aphasia, Frontotemporal Dementia and Other ""Focal Dementias"" 8. ""Retrophylogenesis"" of Memory in Dementia of the Alzheimer Type: A New Evolutionary Memory FrameworkPART THREE: Vascular Dementias and Subcortical Dementias9. Cortical and Frontosubcortical Dementias: Differential Diagnosis 10. Noninfarct Vascular Dementia: The Spectrum of Vascular Dementia and Alzheimer Syndrome 11. The Relationship of Hypertension to Vascular Dementia 12. Vascular Dementias and Alzheimer Disease: Differential Diagnosis 13. Acquired Immunodeficiency Syndrome Dementia ComplexPART FOUR: Depressive Dementias14. Depressive Dementia: A ""Prepermanent Intermediate-stage Dementia"" in a Long-term Disease Course of Permanent Dementia? 15. Depressive Dementia: Cognitive and Biological Correlated and Course of Illness 16. The Nondepressive Pseudodementias 17. Neurobiology of Major Depression in Alzheimer Disease 18. Approaches to the Treatment of Dementing Illness 19. The Spectra of the Dementias Index
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