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Limbic and subcortical brain regions mediate fundamental functions such as memory, emotion, motivation and mood. Limbic and subcortical systems also play a key neurobiological role in other important aspects of human experience, such as substance abuse, reward systems, and religious experience. Most neuropsychiatric disorders involve dysfunction of subcortical structures or the limbic or paralimbic cortex. Dysfunction of temporolimbic systems produces some of the most dramatic and challenging syndromes in clinical medicine. A contribution to the literature on limbic-subcortical systems and neuropsychiatric illness, this text presents and overview of functional limbic anatomy and provides a report on limbic-related syndromes. Part One covers the functional neuroanatomy of limbic and subcortical systems. This emphasis on neuroanatomy provides a foundation for Part Two, which focuses on the limbic system and clinical neuropsychiatric syndromes. Throughout this volume, extensive literature reviews serve as comprehensive reference sources. Many chapters include colour illustrations to depict key points.
Introduction to the neuropsychiatry of limbic and subcortical disorders. Anatomy and Neurochemistry. The limbic system: an anatomic, phylogenetic, and clinical perspective. Ventromedial temporal lobe anatomy, with comments on Alzheimer's disease and temporal injury. The thalamus and neuropsychiatric illness. The accumbens: beyond the core--shell dichotomy. Neurobiology of fear responses: the role of the amygdala. Clinical Syndromes. Paroxysmal limbic disorders in neuropsychiatry. Auras and experiential responses arising in the temporal lobe. Neuropsychiatric symptoms from the temporolimbic lobes. The neurobiology of emotional experience. The neurobiology of recovered memory. The medial temporal lobe in schizophrenia. Limbic-cortical dysregulation: a proposed model of depression. The neurobiology of drug addiction. The neural substrates of religious experience. Index.

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