An undertaking that is as ambitious in its scope as it is masterful in its presentation, Textbook of Autism Spectrum Disorders presents a comprehensive view of the history, etiology, diagnosis, pathophysiology, risk factors, and treatment of this multifaceted groups of disorders. Because more patients are being diagnosed with autism spectrum disorders than ever before, and at earlier ages, research initiatives have been established to address the most critical scientific questions in terms of biological markers, neuroimaging, and treatment efficacy. The resulting deluge of scholarship and research findings has made staying current in the field a daunting task.
To meet the challenge, the editors, among the foremost authorities in the field, have assembled experts from the full range of specialties that are critical to a comprehensive understanding of autism. They have drawn on their clinical experience and scientific knowledge to create this benchmark publication, which includes: * A scientific history of autism, starting from its first identification by Kanner in 1943, that explores the competing theories of etiology and treatment up to the present day, in order to contextualize autism spectrum disorders, both scientifically and culturally* Chapters on clinical evaluation that are presented within a cohesive multidisciplinary framework* Thorough coverage of diagnostic testing and a review of the status of current research on biological markers that brings the reader up-to-date* Chapters on risk factors, both perinatal and environmental, which help to identify areas of potential intervention* Extensive coverage of experimental, novel, and alternative therapies, which may be helpful to patients and their families, as well as provide clinicians with valuable new treatment perspectives* An impressively comprehensive section on treatment options to help clinicians develop cutting-edge skills.
The editors are well aware that a book of this kind could be intimidating, so they have included a number of features that make the text reader-friendly: * A preface and introduction that help to introduce and contextualize the material * Chapter concluding summaries, followed by condensed "Summary Points" that aid the reader in identifying and mastering the most critical information* Liberal use of tables and figures that aid with identification of neurobiological and clinical features, differential diagnoses, drug comparisons, and more
The diversity and breadth of the material make this book an indispensable resource for psychiatrists, psychologists, neurologists, social workers, speech therapists, educators, and patients and their families as well.
ric Hollander, M.D., is Clinical Professor of Psychiatry and Behavioral Sciences and Director of the Compulsive, Impulsive, and Autism Spectrum Disorders Program at the Albert Einstein College of Medicine and the Montefiore Medical Center, Bronx, New York. Previously, he was Esther and Joseph Klingenstein Professor and Chairman of Psychiatry and Director of the Seaver and New York Autism Center of Excellence at Mount Sinai School of Medicine.
Alex Kolevzon, M.D., is Associate Professor of Psychiatry and Pediatrics and Clinical Director of the Seaver Autism Center for Research and Treatment in the Department of Psychiatry at Mount Sinai School of Medicine in New York, New York.
Joseph T. Coyle, M.D., is the Eben S. Draper Professor of Psychiatry and Neuroscience at Harvard Medical School. Previously, he served as the Distinguished Service Professor of Child and Adolescent Psychiatry at Johns Hopkins School of Medicine in Baltimore, Maryland.
PART IAChapter 1. Epidemiology of Autism Spectrum DisordersChapter 2. TBDChapter 3. Pediatric and Neurological AssessmentsChapter 4. Gender Dysphoria, Gender Incongruence, and Sexual IdentityChapter 5. Racial and Ethnic Disparities in Assessment and Evaluation of Autism Spectrum DisorderChapter 6. Digital Biomarkers in Diagnostics and Monitoring of Autism Spectrum DisordersPART IBChapter 7. Social CommunicationChapter 8. Restricted and Repetitive BehaviorsChapter 9. Diet and NutritionPART IIAChapter 10. Genetics and Genomics of AutismChapter 11. EpigenomicsChapter 12. Prenatal, Perinatal, and Parental Risk FactorsChapter 13. Animal Models of Autism Spectrum DisordersChapter 14. Electrophysiological Studies Across ASDsChapter 15. Environmental Toxicity and Immune DysregulationPART IIBChapter 16. Overview of Syndromic Causes of Autism and Commonalities in Neurobiological PathwaysChapter 17. Fragile X Syndrome and Associated DisordersChapter 18. Tuberous Sclerosis ComplexChapter 19. 16p11.2 and Other Recurrent Copy Number Variants Associated With Autism SusceptibilityChapter 20. Rett SyndromeChapter 21. Prader-Willi SyndromePART IICChapter 22. Neuroanatomical Findings in Autism Spectrum DisordersChapter 23. The Amygdala in Autism Spectrum DisordersChapter 24. Neurobiology of ASD Informed by Structural Imaging ResearchChapter 25. Positron Emission TomographyChapter 26. Functional Magnetic Resonance ImagingPART IIIAChapter 27. Serotonergic Medication in Autism Spectrum Disorder (ASD)Chapter 28. AntipsychoticsChapter 29. Treating Hyperactivity in Children With Pervasive Developmental DisordersPART IIIBChapter 30. Complementary and Integrative ApproachesChapter 31. Experimental Therapeutics: OxytocinChapter 32. VasopressinChapter 33. N-AcetylcysteineChapter 34. Arbaclofen: From Animal Models to Clinical Trials in AutismChapter 35. Cannabis, Cannabinoids, and Immunomodulatory AgentsPART IIICChapter 36. Behavioral Treatments for Autism Spectrum DisorderChapter 37. Early Start Denver ModelChapter 38. The Developmental, Individual Difference, Relationship-Based Intervention Model: A Comprehensive Parent-Mediated ApproachChapter 39. Autism Interventions in Schools Mediated by Teachers, Paraprofessionals, and PeersChapter 40. Language and Communication Challenges and Treatments in Autism Spectrum DisorderPART IIIDChapter 41. Transcranial Magnetic StimulationChapter 42. Stem Cell and Gene Therapy for Autism Spectrum DisordersChapter 43. Gene Therapy and Molecular InterventionsPART IVChapter 44. ConsortiumsChapter 45. Employment and Life OutcomesChapter 46. Autism Strengths and NeurodiversityChapter 47. Role of Patient Advocacy Groups in Treatment Development
