Epigenetics—the study of cellular events that affect gene expression without changing the DNA sequence—is having an increasing impact on the field of biology, where it has improved our understanding of the development of pathology and led to novel treatments. The same is true in psychiatry, where epigenetics has provided new perspectives on neurodevelopment across the life span. But although the topic is increasingly present in clinical research (as well as in education, licensing, and board exams), its more complex aspects often exceed the scope of preclinical training.
The essential guide to this growing field of study, Applied Epigenetics for Mental Health Professionals is designed for practicing psychiatrists, nurse practitioners, physician assistants, trainees, and students. Numerous tables and figures, key points that summarize the most pertinent information, and study questions at the end of each chapter are the book’s standout features, reinforcing the specific and broadly applicable information throughout.
Opening with an accessible primer to the major concepts that arise in current applications of epigenetics in psychiatry, the book goes on to examine how epigenetics has improved the understanding of
Mood disorders, with a focus on depression
Neurodevelopmental and neurodegenerative disorders
Trauma, toxic stress, and resilience, and
Health promoting behaviors and aging
Whatever gaps clinicians may have in their knowledge of the core science of epigenetics, Applied Epigenetics for Mental Health Professionals will give them the confidence to incorporate the latest research in the pathology and treatment of psychiatric disorders.
Onoriode Edeh, M.D., is Clinical Assistant Professor of Psychiatry at Central Michigan University College of Medicine, CMU Medical Education Partners, in Saginaw, Michigan.
Kyle J. Rutledge, D.O., Ph.D., graduated from the Psychiatry Residency/Child and Adolescent Psychiatry Fellowship at Central Michigan University College of Medicine, CMU Medical Education Partners, in Saginaw, Michigan, and is working in outpatient clinical practice in Medford, Oregon.
Preface
Acknowledgments
Chapter 1. Overview of Genetic and Epigenetic Mechanisms
Chapter 2. Epigenetic Modulation in Major Depressive Disorder
Chapter 3. Epigenetics in Neurodevelopmental and Neurodegenerative Disorders
Chapter 4. Epigenetics of Childhood Trauma and Resilience
