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Mitochondria in Health and Disease

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Explaining the complex biochemical role of mitochondria in the human body, this book offers practical guidance on how to support clients' mitochondrial function through personalized nutrition to promote increased energy and longevity and tackle a wide range of health complaints. Mitochondria account for 10% of our body weight and, when healthy, provide us with 90% of our body's energy. However, when mitochondria are unhealthy, the consequences on the rest of the body can be serious, contributing to many chronic and degenerative conditions including cancer and Alzheimer's Disease. This insightful book offers tools to help practitioners identify the mitochondrial dysfunction underlying thirteen common diseases and disorders, and guidance on optimising mitochondrial function through diet and nutritional supplementation.
Foreword - Lorraine Nicolle. Part One - Mitochondria: The doorway to understanding the body as a whole. 1. What are mitochondria? 2. Evolution and mitochondria. 3. Energy production. 4. Mitochondrial dynamics: Shape-shifting mitochondria on the move. 5. Mitochondria: The original multi-fuel burners and the need for metabolic flexibility. 6. Acetyl-CoA: Much more than an energy source. 7. Catabolic and anabolic: How mitochondria initiate the change from burning fuel to cell building. 8. Ketone metabolism. 9. Mitochondria and the immune system. 10. Creatine: The mitochondrial ATP assistant. 11. Calcium and mitochondria: Conductors of the cell 'orchestra'. 12. Apoptosis: (Programmed cell death). 13. Iron and mitochondria: A matter of life and death. 14. Urea: Liver mitochondria help to clear ammonia. 15. Health, toxicity and hormesis. Part Two - The influence of mitochondria in disease. 16. Insulin resistance and type 2 diabetes. 17. Hypertension. 18. The heart. 19. Cholesterol metabolism. 20. Autoimmunity and mitochondria: The emerging field of immunometabolism. 21. Fatigue. 22. Neurodegeneration. 23. Cancer. 24. Osteoarthritis. 25. Osteoporosis. 26. Chronic Pain. 27. Depression. 28. Autism Spectrum Disorders.
A thoughtful and thorough explanation of mitochondrial function and the role it plays in generating disease. This book is a combination of the latest scientific research with the practicalities of clinical application, making this book useful guide for practitioners and will certainly assist them in day to day practice.
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