From the Foreword by Candy Cooley, formerly Genetics Awareness Programme Lead at the NHS National Genetics and Genomics Education Centre: "What a delight it is ... to read a book which takes complex scientific concepts and ensures they are understandable by all." With activities and answers, reflection points and a glossary, this interactive textbook supports the 'Fit for Practice in the Genetics Era' competence framework, offering an introduction to the theory of genetics and then using common genetic conditions/disorders as case studies to help students apply theory to practice and examine the service user experience. Genetics is written by an experienced teacher of health care sciences and is ideal for student nurses who need to demonstrate and apply knowledge of genetics and genomics. It is also suitable for other health care students and for qualified practitioners who would like to refresh their knowledge of the subject. From lecturer reviews: "A well written and nicely laid out genetics text at an appropriate level for adult nursing students." "Fabulous text, student friendly."
Karen Vipond's career experiences have been very varied as she has worked as a biologist, teacher, trauma nurse, district nurse, health visitor, and medical research coordinator for Oxford University and the World Health Organisation. She has combined her different careers as a biologist and a nurse in order to teach biological sciences to health care professionals. She was a lecturer at the School of Healthcare Sciences at Bangor University and is now a tutor for the Open University School of Health, Wellbeing & Social Care.
Foreword; Introduction 1. Basic cell biology 1.1 Introduction 1.2 Chromosomes 1.3 Chromosomal inheritance 1.4 Genetic information 1.5 Protein 1.6 Mitochondrial DNA 1.7 The classification of genetic material 2. Inheritance 2.1 Introduction 2.2 Exceptions to the rules 3. Autosomal recessive and dominant inheritance 3.1 Introduction 3.2 Autosomal recessive inheritance 3.3 Autosomal dominant inheritance 3.4 Classification of gene action 3.5 Co-dominance 3.6 Multiple alleles 3.7 Lethal alleles 4. Sex-linked inheritance 4.1 Introduction 4.2 The X chromosome 4.3 The Y chromosome 4.4 Sexual development 4.5 The inheritance of sex 4.6 Sex-linked inheritance 4.7 X inactivation 4.8 Sex-linked genetic effects 5. Two or more genes 5.1 Introduction 5.2 Monogenic inheritance 5.3 Polygenic inheritance 5.4 Multifactorial inheritance 5.5 Common multifactorial disorders 5.6 Identifying the genes in multifactorial conditions 6. Mutations 6.1 Introduction 6.2 Chromosomal mutations 6.3 Gene mutations 7. Pedigree analysis 7.1 Introduction 7.2 Modes of inheritance 7.3 Problems with pedigree analysis 8. Clinical applications 8.1 Screening and testing 8.2 Gene therapy 8.3 Pharmacogenetics 9. Cancer genetics 9.1 Introduction 9.2 Oncogenes 9.3 Tumour-suppressor genes 9.4 Environmental triggers 9.5 Other cancer considerations 10. Genetic counselling 10.1 Introduction 10.2 UK genetic services 10.3 Genetic counselling 10.4 Becoming a genetic counsellor 10.5 Making an appropriate referral 10.6 Genetic counselling for tests 10.7 Ethical issues 10.6 Internet resources for genetic education Answers to the activities; Glossary; Index
