Clinical Epidemiology & Evidence-Based Medicine

SECTION I: PRINCIPLES OF CLINICAL REASONING Of Patients & Populations: Population-Based Data in Clinical Practice Test Performance: Disease Probability, Test Interpretation & Diagnosis Quantitative Aspects of Clinical Thinking: Predictive Values and Bays' Theorem Fundamentals of Screening: The Art and Science of Looking for Trouble Measuring and Conveying Risk SECTION II: PRINCIPLES OF CLINICAL RESEARCH Hypothesis Testing 1: Principles Hypothesis Testing 2: Mechanics Study Design Interpreting Statistics in the Medical Literature SECTION III: FROM RESEARCH TO REASONING: THE APPLICATION OF EVIDENCE IN CLINICAL PRACTICE Decision Analysis Diagnosis Management APPENDICES

"The presentation is consistently excellent. One, the writing is lucid and organized in a way that should be very natural for the clinical reader. Two, the text requires no background in mathematics and uses a minimum of symbols. And, three, the methodological concepts and clinical issues are well integrated through a number of carefully prepared and comprehensive examples." -- Greg Samsa