This timely volume reviews current data on the effects of estrogen on the central nervous system, highlighting clinical aspects of this topic. Experts from the fields of psychiatry, pharmacology, neurology, and geriatrics collaborate to clarify the known risks and benefits of hormone therapy and explore questions that remain to be elucidated.Among the topics discussed: '' Preclinical data on estrogen's effects on cognitive performance '' The short-lived effects of hormone replacement therapy on cognitive function '' Structural and functional brain imaging data regarding estrogen's effects on the central nervous system '' Preclinical efforts to develop effective NeuroSERMs for the brain '' The effects of estrogen on moodCiting the ongoing confusion over the risks and benefits of estrogen therapy, the contributors emphasize the need for additional research on medication, doses, preparations, methods of administration, alternative therapies, and supplements. This volume educates researchers, clinicians, and students on the current knowledgeincluding the effects of estrogen on mood, cognition, and brain metabolismand provides guidelines for clinical practice and future research. 16 line drawings, 4 halftones.
