Preface - Clyde B McCoy, Lisa R Metsch, and James A Inciardi PART ONE: THE SCOPE OF THE PROBLEM The Epidemiology of Drug Use among American Youth - Lana D Harrison and Anne E Pottieger Risk and Protective Factors for Drug Use - Judith S Brook and David W Brook Etiological Considerations Modeling Adolescent Health Behavior - Lilly M Langer The Preadult Health Decision-Making Model PART TWO: PREVENTION INITIATIVES Prevention Technologies for Drug-Involved Youth - Mario A Orlandi DARE (Drug Abuse Resistance Education) - Richard R Clayton et al Very Popular but Not Very Effective Religious Belief and the Initiation and Prevention of Drug Use among Youth - Duane C McBride, Patricia B Mutch, and Dale D Chitwood PART THREE: TREATMENT INITIATIVES Juvenile Health Service Centers - Richard Dembo and James E Rivers An Exciting Opportunity to Intervene with Drug-Involved and Other High-Risk Youth Issues and Intervention - Sally J Stevens et al Substance Abuse Treatment for Adolescents Using a Modified Therapeutic Community Model PART FOUR: INTERNATIONAL PERSPECTIVES Drug Use, HIV Risks, and Prevention/Intervention Strategies among Street Youths in Rio de Janeiro, Brazil - Hilary L Surratt and James A Inciardi Drug Use and HIV among Youth in Manipur, India - Swarup Sarkar et al