IntroductionDaniel CallahanAssessments of Efficacy in Biomedicine: The Turn toward Methodological PluralismKenneth F. ShaffnerCAM and Cultural Diversity: Ethics and Epistemology ConvergeDavid J. Hufford The Role of Science in Assessing Conventional, Complementary, and Alternative MedicinesLoretta M. KopelmanPersonal Experience, Popular Epistemology, and Complementary and Alternative Medicine ResearchBonnie B. O'ConnorThe Placebo Effect: Implications for the Study and Practice of Complementary and Alternative MedicineHoward BrodySpirituality in Clinical Care: A Brief Review of Patient Desire, Physician Response, and Research OpportunitiesDavid B. Larson and Susan B. LarsonInterpreting Results from Randomized Clinical Trials of Complementary/Alternative Interventions: The Role of Trial Quality and Pre-trial BeliefsAsbjorn Hrobjartsson and Stig BrorsonEvidence, Ethics, and the Evaluation of Global MedicineWayne B. JonasThe Nature of Evidence in Complementary and Alternative Medicine: Ideas from Trials of Homeopathy in Chronic HeadacheTom Whitmarsh Medical Culture and CAM Culture: Science and Ritual in the Academic Medical CenterPaul Root Wolpe The Quest for Holism in MedicineAlfred I. TauberContributors Index