Preface I. Background and Context 1. Epidemiological and Methodological Issues in Neuropsychological Research on PTSD, Lisa M. Duke and Jennifer J. Vasterling II. Biological Perspectives 2. Neurobiological and Neurocognitive Alterations in PTSD: A Focus on Norepinephrine, Serotonin, and the Hypothalamic-Pituitary-Adrenal Axis, Steven M. Southwick, Ann Rasmusson, Jill Barron, and Amy Arnsten 3. Structural and Functional Anatomy of PTSD: Findings from Neuroimaging Research, Lisa M. Shin, Scott L. Rauch, and Roger K. Pitman 4. Electrophysiology of PTSD, Linda J. Metzger, Mark W. Gilbertson, and Scott P. Orr III. Cognitive and Information-Processing Perspectives 5. Information-Processing Biases in PTSD, Joseph I. Constans 6. Encoding and Retrieval of Traumatic Memories, Chris R. Brewin IV. Developmental and Population-Specific Perspectives 7. Early Trauma Exposure and the Brain, Michael D. De Bellis, Stephen R. Hooper, and Jennifer L. Sapia 8. Neuropsychological Findings in Adults with PTSD, Jennifer J. Vasterling and Kevin Brailey 9. Learning and Memory in Aging Trauma Survivors with PTSD, Rachel Yehuda, Karina Stavitsky, Lisa Tischler, Julia A. Golier, and Philip D. Harvey 10. PTSD and Traumatic Brain Injury, Allison G. Harvey, Michael D. Kopelman, and Chris R. Brewin V. Clinical Applications 11. Clinical Neuropsychological Evaluation, Jennifer J. Vasterling and Jennifer S. Kleiner 12. Implications for Psychological Intervention, Chris R. Brewin 13. Pharmacological Approaches to Cognitive Deficits Associated with PTSD, Matthew J. Friedman