Plunkett's Biotech, Pharmaceuticals & Genetics Industry Almanac 2027

Jack W. Plunkett is CEO & Publisher of Plunkett Research, Ltd., a Houston-based provider of market research and industry information in printed and electronic formats. Plunkett Research provides analysis, statistics and other vital data on all major industry sectors, from InfoTech to Retailing to Banking and Internet of Things. Plunkett's client list includes 10,000 leading corporations, universities and government agencies worldwide. Plunkett's products are distributed electronically through subscriptions to its online service, and around the globe by major distributors, including ThomsonReuters.Jack Plunkett is the author of numerous books, including the gold medal-winning The Next Boom: What you absolutely, positively have to know about the world between now and 2025. Plunkett is frequently interviewed as an expert source by publications such as Time magazine, Forbes, The Wall Street Journal, The New York Times and Investor's Business Daily, media outlets such as NPR's Marketplace, ABC, and Marketwatch, as well as local and regional newspapers and national columnists. Plunkett received an Academic Book of the Year Award for his Plunkett's Health Care Industry Almanac, and he was a regional finalist in the Entrepreneur of the Year Awards sponsored by EY.

Introduction 1 How to Use This Book 3 Chapter 1: Major Trends Affecting the Biotech, Pharmaceuticals & Genetics Industry 7 1) Major Trends Affecting the Biotech, Pharmaceuticals & Genetics Industry 8 2) The State of the Biotechnology Industry Today 8 3) A Short History of Biotechnology 11 4) Fast Track Drugs Come to Market in the U.S. with FDA Cooperation 13 5) Ethanol Production Is Massive for Fuel Additives 14 6) Cellulosic Ethanol Makes Slow Commercial Progress 14 7) Major Drug Companies Acquire or Partner With Smaller Biotech Firms 15 8) Pharmaceutical R&D Improves with Artificial Intelligence (AI) 15 9) Nations Compete Fiercely in Biotech Development/China Ranks as Major Center 16 10) Patients' Genetic Profiles Plummet in Price as DNA Sequencing Technologies Advance 17 11) Gene Therapies Target Defective Genes/CRISPR Advances DNA Editing 18 12) Vaccines & Viruses as Therapies/mRNA and Dendritic Cells Show Great Promise 20 13) Massive R&D Investment Required for Development and Approval of New Drugs/Drug Prices Soar 22 14) Generic Drugs Have Biggest Market Share by Unit Volume, but not by Total Revenues 23 15) America Pays Higher Prices for Drugs Than Other Nations/U.S. Government Launches Drug Price Negotiation and Control Powers for Medicare 25 16) Biotech and Orphan Drugs Create New Revenues for Drug Firms 26 17) Revolutionary New Drugs (Zepbound, Wegovy and Ozempic) Treat Obesity, Diabetes and Addiction/Show Promise for Treating Many Other Diseases 27 18) Biosimilars (Generic Biotech Drugs) Receive FDA Guidelines for Accelerated Approval/Competition Will Be Fierce 28 19) Market for CBD Remains Steady 29 20) Stem Cells and 3-D Printing-A New Era of Tissue Replacement Takes Shape 30 21) Genetically Modified (GM) Seeds and Crops Planted in Dozens of Nations/Agribio R&D Investment Is High 32 22) Genetically Modified (GM) Foods Prompt Controversy, Labeling and Legislation 33 23) Plant-Based Meat Substitutes Developed 33 24) Selective Plant Breeding, Mutagenesis and Gene-Editing, Including CRISPR, as Alternatives to GM Seeds 34 25) Immunotherapy, ADCs and CAR-T Create Exciting New Approach to Fighting Cancers 35 26) Technology Discussion-Genes and DNA 37 27) Technology Discussion-Proteins and Proteomics 38 28) Technology Discussion-DNA Chips 38 29) Technology Discussion-SNPs ("Snips") 39 30) Technology Discussion-Recombinant DNA 39 31) Technology Discussion-Polymerase Chain Reaction (PCR) 39 32) Technology Discussion-CRISPR 39 33) Technology Discussion-mRNA 40 Chapter 2: Biotech, Pharmaceuticals & Genetics Industry Statistics 41 Biotech Industry Statistics and Market Size Overview 42 The U.S. Drug Discovery & Approval Process 43 U.S. FDA Novel New Drug Approvals by Year 2016-2025 44 Employment in Life & Physical Science Occupations by Business Type, U.S.: May 2025 45 Federal R&D & R&D Funding for Basic Research, U.S.: Fiscal Years 2024-2026 46 U.S. Exports & Imports of Pharmaceutical Products: 2020-2025 47 Prescription Drug Expenditures & Annual Percent Change, U.S.: 2018-2034 48 NSF Budget by Appropriation (Dollars in Millions), Fiscal Years: 2025-2027 49 Research Funding for Biological Sciences, U.S. National Science Foundation: Fiscal Years 2025-2027 50 The Nation's Health Dollar: 2026 Where It Came From (Projected) 51 The Nation's Health Dollar: 2026 Where It Went (Estimated) 52 Chapter 3: Important Biotech, Pharmaceuticals & Genetics Industry Contacts 53 (Addresses, Phone Numbers and Internet Sites) Chapter 4: THE BIOTECH 350: Who They Are and How They Were Chosen 91 Index of Companies Within Industry Groups 92 Alphabetical Index 100 Index of U.S. Headquarters Location by State 103 Index of Non-U.S. Headquarters Location by Country 106 Individual Profiles on Each of THE BIOTECH 350 109 Additional Indexes Index of Hot Spots for Advancement for Women/Minorities 442 Index by Subsidiaries, Brand Names and Selected Affiliations 444 A Short Biotech, Pharmaceuticals & Genetics Industry Glossary 457