Preface to the third edition; Acknowledgements 1 Health economics 2 Thinking like an economist 3 Cost minimization analysis 4 Cost-effectiveness analysis 5 What do we mean when we say 'value'? 6 Quality of life 7 Health utilities 8 The infamous quality-adjusted life year (QALY) 9 Cost utility analysis 10 Evidence-based medicine 11 Critical appraisal 12 Systematic reviews and meta-analyses 13 Health technology assessment and the UK's approach 14 Health technology assessment - an international comparison 15 Health technology assessment in the USA 16 Health technology assessment in the USA - The Institute for Clinical and Economic Review (ICER) 17 Health technology assessment and medical devices Glossary; Index