I. Research Issues in Advanced Dementia 1. Methodological Considerations 2. Severity of Dementia 3. End-of-Life with Dementia II. Assessing Outcomes of Interventions to Promote Well-Being 4. Quality of Life in Late-Stage Dementia Myron F. Weiner, M.D. Linda S. Hynan, Ph.D. 5. Engagement in Dementia Cameron J. Camp, Ph.D. Michael J. Skrajner, M.A. Gregg J. Gorzelle 6. Comfort in Advanced Dementia 7. Pain in Dementia 8. Quality of Family Visits with Residents Who Have Dementia III. Evaluation of Interventions to Alleviate Troublesome Symptoms 9. Behavioral Symptoms of Dementia 10. Agitation in Dementia 11. Rejection of Care in Dementia with Ellen K. Mahoney, R.N., Ph.D. Index